Debendra Mohan Bose was born in Calcutta (present day Kolkata) in a famous Brahmo family.

He was the youngest son of Mohini Mohan Bose, one of the first Indians to proceed to USA to qualify himself in field of homeopathy.

He worked as a research scholar under Jagadish Chandra Bose for one year, during which he participated in his uncle's biophysical and plant physiological investigations.

In 1914, D M Bose was appointed the Rashbehary Ghosh Professor of Physics in the newly founded Calcutta University College of Science.

He gave Satyendra Nath Bose two books of Max Planck, Thermodynamik and Warmestrahlung (unavailable in India then).

[2] A discussion during the 1938 Science Congress Session prompted D. M. Bose and his colleague Bibha Chowdhuri[4] to study cosmic rays using photographic plates.

Walther Bothe gave the duo the idea of considering photographic emulsion as a continuously active cloud chamber to register and store tracks.

Due to the World War II restrictions, full tone photographic plates were not available in India at that time.

In Europe, Cecil Frank Powell independently used exactly the same method to identify the new particle pi-meson (now pion), but with improved full-tone photographic emulsion plates.

He was a dedicated worker of the Sadharan Brahmo Samaj and was served several years as its office bearer (President, Secretary & Treasurer).

In 1927 at the occasion of the 100th death anniversary of Italian physicist Alessandro Volta, in Como, a conference was organized (as mentioned above).