Delta Profronde was a single-day road bicycle race held annually in June in Zeeland, Netherlands.

In 2005, the race was organized as a 1.1 event on the UCI Europe Tour.

It was previously known as Ronde van Midden-Zeeland and it was an amateur race between 1959 and 1973.

In 2008, the organizers of the Delta Profronde and of the OZ Wielerweekend operated a fusion to create the stage race Delta Tour Zeeland.

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