[5] Prior to the 2016 MLB draft, Pérez won the Most Valuable Player award in the Víctor Pellot Excellence Tournament, guiding his team to the championship by batting .556 (including several extra-base hits) and leading the tournament in RBIs and runs scored before the highest ranked prospects in Puerto Rico.

[9] After signing, Pérez made his professional debut with the Rookie-level Gulf Coast League Cardinals where he batted .294 with a .745 OPS and 12 stolen bases.

He spent 2018 with the State College Spikes of the Low–A New York–Penn League, batting .213 with one home run, 21 RBIs, and eight stolen bases over 64 games.

[17] Over the 2020-21 offseason, Pérez gained over twenty pounds and changed his diet, attributing his struggles throughout his professional career to his "skinny" figure.

[18] He spent the 2021 season with the Springfield Cardinals of the Double-A Central, slashing .265/.322/.339 with four home runs, 23 RBIs, and 24 stolen bases over 98 games.