As of December 31, 2021, Denbury had 191.689 million barrels of oil equivalent (1.17273×109 GJ) of estimated proved reserves, of which 98.6% was petroleum and 1.4% was natural gas.

The company also had an estimated 910 billion cubic feet of probable carbon dioxide reserves at Jackson Dome.

The company's largest producing property was the Cedar Creek Anticline in Montana and North Dakota, which accounted for 23% of production in 2021.

The company's shares rose sharply in pre-market trading, but fell after Denbury said the earlier press release was "completely fraudulent".

[20] In 2011, a carbon dioxide pipeline owned by the company had a "blowout" in Tinsley, Mississippi, causing the sickening of one worker and killing deer, fish and birds.

[26] In March 2023, Denbury signed a consent order to reform their safety procedures and response protocols.