[2] She is a Democrat and the first female Native American elected to statewide office in the United States.

[6] On November 4, 2015, Juneau announced her candidacy for the United States House of Representatives in the 2016 congressional election.

Juneau shifted her career path, attending the University of Montana Law School and completing her J.D.

She was a high school teacher in New Town, North Dakota, within the Fort Berthold Indian Reservation, from 1994 through 1995, and in Browning, Montana, from 1995 through 1997.

It was designed to deliver education in the public schools on Montana's American Indian heritage.

[10][11] Juneau was a law clerk at the Montana Supreme Court for justices Jim Regnier and Brian Morris from 2004 through 2005.

[12] In the November general election, the final vote tally was 234,483 for Juneau (51%), 201,091 (43.7%) for her GOP opponent, Elaine Sollie Herman, and 24,236 (5.3%) for Libertarian candidate Donald Eisenmenger.

[16] Juneau was named as a possible candidate for US Senator Max Baucus's (D-Montana) seat, which was vacated upon his retirement in 2014.

[18] As of November 1, 2016, she ranked 6th in the country for congressional candidates raising money from donors giving $200 or less.

[22][23] Juneau gave a speech at the 2012 Democratic National Convention in which she praised U.S. President Barack Obama's education policy.