Denison is a city in Jackson County, Kansas, United States.

[3] Denison was founded as a result of the Kansas City, Wyandotte and Northwestern Railway laying tracks that would connect the communities of Valley Falls and Holton.

The railroad was slated to come through one mile south of an existing village, Tippinville, and in September 1887, A.D. Walker and Hollis Tucker, land speculators, laid out lots for a new town, which was named after Tucker's hometown of Denison, Ohio.

It was a truly exciting event for school children when Buffalo Bill came to Denison to visit his niece, Nellie Myers Copas, and her family.

[citation needed] A post office, named North Cedar, was established in 1867.

The first school, built of logs, was established in 1858 south of present-day Denison, on the site of the North Cedar Cemetery.

[citation needed] The Denison State Bank was founded in 1901, and after its second robbery, in 1938, was moved to Holton, the county seat, where it thrives today under the same name.

The Denison Rural High School was established in 1916, and a brick building was erected.

However the school continued to serve lower grades until it closed its doors in 1990.

[citation needed] According to the United States Census Bureau, the city has a total area of 0.11 square miles (0.28 km2), all land.

[4] Denison is part of the Topeka, Kansas Metropolitan Statistical Area.

The 2020 United States census counted 146 people, 63 households, and 42 families in Denison.

The racial makeup of the city was 96.3% White, 0.5% Native American, and 3.2% from two or more races.

The community is served by Holton USD 336 public school district.