Dennie–Marfan syndrome is a syndrome in which there is association of spastic paraplegia of the lower limbs and mental retardation in children with congenital syphilis.
[1] Both sexes are affected, and the onset of the disease can be acute or insidious, with slow progression from weakness to quadriplegia.
Epilepsy, cataract, and nystagmus may also be found.
[citation needed] The syndrome was described by Charles Clayton Dennie in 1929,[2] and Antoine Marfan in 1936.
This article about a medical condition affecting the nervous system is a stub.