Dennis "Doc" O'Keefe (born April 1944) is a Canadian politician who served as the 14th mayor of St. John's from 2008 to 2017 in Newfoundland and Labrador, Canada.

[2][4] O'Keefe was challenged by his deputy mayor Ron Ellsworth and local reggae singer and organic farmer Mark Wilson in the 2009 municipal election.

However, Nova Scotia Member of Parliament Peter MacKay became Newfoundland and Labrador's de facto minister in the federal cabinet.

[8] Several months later O'Keefe called for the provinces MPs to vote against Harper's minority government's 2009 budget, which provincial politicians said attacked Newfoundland and Labrador.

[9] in 2012, O'Keefe criticized the federal budget for the public service jobs that were cut in the city and later said he was looking forward to the day that Harper would not be prime minister.