The Denver Dry Goods Company Building is a historic department store building located in downtown Denver, Colorado.

A description on one postcard from 1916 read: "The Largest Store in the Central West, 400 Feet long-Seven Acres Floor Area, 1,200 Employees, A $1,500,000 Stock, 15th to 16th on California Street Denver Colorado".

The flagship store of The Denver Dry Goods Company, the retailer was part of Associated Dry Goods, and under ADG the downtown Denver store was renovated.

The store was acquired by May Company as part of Associated Dry Goods Corp. in 1986.

Originally built in 1889, the store was expanded in 1898, 1906 and 1924.