[6] In the 21st century, the teams have generally experienced opposite fortunes, first with Espanyol thriving while Barcelona battled relegation, a period lasting until 2012 – the year Espanyol lifted the Copa de la Reina and Barcelona won the league – before Barcelona began its domination and Espanyol struggled.

[4][7] In January 2021, the derby was held at the Camp Nou to celebrate 50 years since the first game, also played at the stadium.

[8] At the end of this season, Espanyol was relegated and Barcelona won a continental treble, both for the first time.

In the 21st century, significant overlap was caused when Barcelona restructured their women's section in 2006–07.

The youth teams were disbanded, with many of the 80 young players taken into Espanyol's stronger youth structure,[10][11] and the women's team struggled, causing players to leave, including to Espanyol.