From ages 6 to 14, Nixon worked on many regional commercials including Six Flags Fiesta Texas, San Antonio Hispanic Chamber of Commerce, and Southwestern Bell.

Nixon's first network television credit was a role in the 1999 airing of the America's Most Wanted episode titled "The Jason Crawford Killing".

In January 2007 Nixon produced and starred in a sci-fi thriller, The Lights, directed by John M. Sjogren, where he played the lead character, with Ozzy Lusth from Survivor and Joe Estevez.

In , Nixon signed onto the teen comedy The Jerk Theory; he stars alongside Josh Henderson, Jenna Dewan, and Tom Arnold, it was released February 7, 2009.

Nixon produced and starred in the multi award-winning film A Schizophrenic Love Story alongside Academy Award nominee Bruce Davison in 2010.

Nixon made his directorial debut in 2011 with the horror–comedy spoof Supernatural Activity with a release date in October 2012 and also starring in Butcher Boys, working with horror writer Kim Henkel the same year.

Nixon was the producer on Jeffrey Reddick's (creator of the Final Destination franchise) feature film Dead Awake, which was released theatrically May 15, 2017.