Derek St. Holmes (born February 24, 1953) is an American rock musician, best known as the lead singer and rhythm guitar player for Ted Nugent's early solo career.

The Amboy Dukes and their guitar player Ted Nugent had already recorded several albums and were a staple of the Midwest rock scene at the time.

He is the lead vocalist on the three most popular recordings from the debut album: "Hey Baby" (also composed by St. Holmes), "Stranglehold" and "Just What the Doctor Ordered".

[3] St. Holmes remained in Nugent's band for the 1977 album Cat Scratch Fever and its subsequent tour which produced the 1978 Double Live Gonzo!

In 1979, St. Holmes joined up with Ted Nugent's bass player Rob Grange and ex-Montrose drummer Denny Carmassi to form St. Paradise.

In 1983, St. Holmes contributed vocals to one song on the Michael Schenker Group release Built to Destroy, and also appeared on the live follow-up, Rock Will Never Die.

However, frequent long trips to England and Europe had St. Holmes wanting to return home to the US, where he had a wife and newborn child, and he departed MSG amicably.

After another departure from Nugent, St. Holmes co-founded the supergroup Big People in 1999, which also included guitarist Pat Travers, bassist/vocalist Benjamin Orr (The Cars), guitarist/vocalist Jeff Carlisi (.38 Special) and drummer Liberty DeVitto (Billy Joel).

On December 27, 2008, St. Holmes was a special guest at a Get the Led Out concert at Ram's Head Live in Baltimore, Maryland.

The CD includes other artists such as HiFi Superstar, Doogie White, Eric Martin, Troy Luccketta, Jeff Pilson, Randy Jackson, Rachel Barton, Rex Carroll, Kimberley Dahme, and The 77's.

[7] St. Holmes performed at the 2015 Dick Wagner Memorial "Remember the Child" benefit concert in Detroit, and he co-headlined the same event in 2016 with Brad Whitford and The Frost.

[8] In 2017, St. Holmes surprised fans by joining an REO Speedwagon performance for an impromptu rendition of "Stranglehold" during the annual NAHA (Native American Heritage Assoc) benefit Rock Legends Cruise.