Desdemona Sands Light was a lighthouse located on the Pacific coast of the U.S. state of Oregon, at the mouth of the Columbia River to aid navigation of the Columbia Bar.

The Lightship Columbia kept station about 5 miles (8.0 km) offshore.

Its design by Carl Leick is identical to that of Semiahmoo Harbor Light near Blaine, Washington, a 1+1⁄2-story dwelling built on a cluster of pilings in 12 feet (3.7 m) of water[3] with a rooftop tower housing the light and a fog signal.

It was one of the last U.S. wooden pile foundation lighthouses built.

Only the lightkeeper was present; there was a small boat to reach the mainland, where the keeper's family lived.