The desert pygmy mouse (Mus indutus) is a species of rodent in the family Muridae.

It is found in Angola, Botswana, Namibia, South Africa, Zambia, and Zimbabwe.

Its natural habitats are dry savanna and subtropical or tropical high-altitude grassland.

The desert pygmy mouse is territorial, but it can be found singularly, in pairs or in groups.

For Desert pygmy mice in captivity some cases of cannibalism were observed.