Desmond's stores in Northridge and West Covina were liquidated only in 1986 and survived in Palm Springs into the first years of the 21st century.

Desmond moved his store to its fourth location, in the Bryson Block, 141 S. Spring St. at the northwest corner of 2nd St., which only ten years earlier had been considered "the country".

[19] In 1906,[19] when it moved again across the street to the Douglas Building at 301 S. Spring St., its sixth home, as one of the largest retailers in Los Angeles at that time.

Around this time Desmond's became a store of reference across Southern California, well known for a broad range of high quality men's attire.

Meanwhile, it opened locations across the Western United States:[60] Northridge and West Covina stores continued operating until 1986.

[3] Kapelovitz sold the Palm Springs La Plaza store to Frank Gross and Stanlee McNeish, and it continued under the Desmond's name until 2005.

[42] A separate "Desmond's Big and Tall" Store in Palm Desert Town Center continued operating after that time.