The group remained an independent band their entire career and experienced frequent line-up changes until going on indefinite hiatus in 2015.
[7] Destrose announced they would temporary suspend activities after their September 25 concert at Meguro Live Station and that it would be their last with Nene, Nana and guitarist Satty.
[2][10] Destrose resumed activities after the January 9, 2012 Women's Power 20th Anniversary concert, where they played alongside Show-Ya, Aldious and Babymetal.
[17] The band's only studio album, the self-titled Destrose, was released on April 10, 2013 and supported by a fourteen-date Japanese tour that ended with their first one-man concert on June 1 at Meguro Live Station.
[19] They were the only indie band at Show-Ya's female artists-only Naon no Yaon 2013 festival on April 29, which also included Scandal and Cyntia among others.
[26] Drummer Haruna left the band after her farewell concert on December 24 at Meguro Rock-May-Kan due to her upcoming marriage.
[30][31] In February, leader and sole constant member Mina left the band due to her ongoing health issues.
[33] They played their final concert, titled Persistence of Rose, at Meguro The Live Station in Tokyo on July 18, 2015.
[36][37] Their 2019 EP Headless Goddess is composed almost entirely of re-recorded Destrose songs and features guest vocalists, including Ibuki.