The Detroit–Windsor area acts as a critical commercial link straddling the Canada–United States border and has a total population of 5,976,595.

[4] Many federal, state and provincial bi-national agreements affecting trade and border security also link the region.

The joint Royal Canadian Mounted Police and U.S. Coast Guard Shiprider program of marine border security are examples.

[5] The increasing interdependence of Detroit–Windsor was recognized by U.S. regional business and government in 2007 when Windsor Mayor Eddie Francis was invited to take part in, and speak at, the annual Mackinac Policy Conference, a committee of regional business and political leaders, developed to address the economic and quality of life concerns that matter most to Southeast Michigan.

As an example, Caesars Windsor casino, the largest in Canada, attracts visitors from the Metro Detroit region.

[7] Moreover, Windsor's economy has continued to diversify with several hundred green-energy jobs having been created as of June 2011.

Windsor Airport is currently undergoing a major expansion, with an aircraft maintenance and repair hangar being constructed, as well as cargo facilities for air to rail/road transport.

Professions identified in the 1988 Free Trade Act are permitted TN Visas for legal work in the United States and Canada.

[11] It is the second largest border region in the world, after Kinshasa-Brazzaville in Central Africa, with some 5,700,000 people living in its metropolitan area.