The player uses a touchscreen to move Adam Jensen, a protagonist from the cyberpunk-themed series, as a puzzle piece through a board game while avoiding obstacles and manipulating the environment.

But compared to the other entries in the Go series, reviewers considered Deus Ex Go's to be less creative, with a lackluster story, less visually interesting aesthetic, and shorter length.

Embracer Group, following their acquisition of Square Enix Montréal, announced that Deus Ex Go would be removed from app stores with its servers shut down on January 4, 2023.

[2] The player touches the screen to move Adam Jensen, a protagonist from the stealth combat, cyber-dystopian Deus Ex series, between nodes on a hexagonal grid towards an exit.

[3][4][5] If moved to a specific node, the character will stealthily take down guards, hack computers, and activate his human augmentations, such as invisibility.

The character can store a power-up to move for two turns without detection while in an enemy's line of sight, activate terminals remotely, or use projectile attacks against guards on distant nodes.

[7] As part of a tie-in with Deus Ex: Mankind Divided, players complete the main story and weekly puzzles in the mobile game to unlock perks in the console title.

Their combination was expected to resolve philosophical differences between the teams stemming from indie and AAA traditions of game development and pricing.

[17] Embracer Group, following their acquisition of Square Enix Montréal, announced that Deus Ex Go would be removed from app stores with its servers shut down on January 4, 2023.

[8][7][20][22] Compared to the other entries in the Go series, reviewers considered Deus Ex Go's added story to be lackluster, its aesthetic to be less visually interesting, and its length to be shorter.

[7] Among the most satisfying moments in the Go series, the IGN and TouchArcade reviewers appreciated the game mechanic of determining how best to use a hack or drone to slip past enemies.

[22] IGN wrote that the game's story and environments remained in the background and were ultimately forgettable, or in the case of the former, a hindrance,[8] especially when the scenes could not be skipped on later replays.