Doctor Devi was born at NYU Medical Center (where she now teaches[1]) to Mary and Joseph Nampiaparampil, Catholic Indians who had immigrated to the U.S. from Kerala, India.

Doctor Devi began working for the U.S. Department of Veterans Affairs in 2008 and started the Brain Injury Clinic at the VA Central California in Fresno.

She moved to New York City in 2009 to direct and develop the Pain Management program at the VA Hudson Valley.

She established the Veterans' Hospital in Manhattan (the VA New York Harbor) as a referral center for invasive pain procedures.

She made her debut as a medical expert on television on The Dr. Oz Show when she demonstrated botox injections for chronic migraine pain in front of a live audience.

She published a related article in Newsweek entitled "How a Death Row Inmate's Request to Give His Organs Kept Him Alive".

She won the republican primary, losing in the general election to incumbent democrat Jumaane Williams.