[1] Harry Seeley had found his fossil in the Burgersdorp Formation of the Beaufort Group in the Karoo Basin of South Africa.

[5] Until a study performed by Botha and colleagues in 2005, the post cranial skeletons of Diademodon and its close relative, Cynognathus were near to impossible to distinguish.

Another interpretation of this data was that Diademodon may have had hippo-like behavior, that is, it remained in deep pools of water during day hours and only left its aquatic environment at night to forage for food.

However, this idea was put to rest as Diademodon did not morphologically or isotopically reveal any adaptations for long term aquatic life.

A third suggested possibility was that Diademodon may have been close to readily available water sources, though did not spend the majority of its life in them.