Some sources claim she obtained a law degree from the Romanian-American University in Bucharest, and then worked for Eugen Dijmărescu [ro], Minister of Commerce in the Năstase cabinet.

[13][14] On 21 December 2020, she was elected to the Senate of Romania for the Iași County as a member of Alliance for the Union of Romanians (AUR).

This meeting had not been approved for representation by the Parliament leadership and one of the MPs, PSD member Dumitru Coarnă, was expelled from his party shortly afterwards.

[27][28] Additionally, Șoșoacă was appreciated by Killnet (a pro-Russia hacking group which launched in 2022 a series of cyberattacks on multiple Romanian websites), after she said that Romania must not get involved in the war in Ukraine.

[30] In retaliation, Ukraine announced it would impose sanctions against Șoșoacă, labeling her as a threat to Ukrainian national security.

[31] On 21 November 2023, Diana Șoșoacă interrupted a secret session of the Parliament of Romania, during which footage of the Israel–Hamas war was presented, screaming "Palestine".

[36] On the first day of the Strasbourg Plenary, Șoșoacă wore a muzzle over her face as a sign of dissent during Ursula von der Leyen's opening speech.

[5] In response, she claimed "[t]his proves the Americans, Jews and the European Union have plotted to rig the Romanian election before it has begun".

[40] On 12 December 2021, Șoșoacă was interviewed by Italian reporter Lucia Goracci who was investigating the anti-vaccine movement for Rai 1.

After a very tense exchange, Șoșoacă locked the door of her apartment and called the police, claiming that someone had entered her office.

31/2002[44] after several people, including Șoșoacă, commemorated Iron Guard leader Corneliu Zelea Codreanu at a wayside cross in Tâncăbești.