Future Academy Award winner Jennifer Jones co-stars as Gwen Andrews, credited here under her birth name of Phyllis Isley.

In the comic strip, Dick Tracy is actually a detective in the police force of an unnamed Midwestern city resembling Chicago.

International spy, Zarnoff, in the employ of "The Three Powers" (presumably a fictionalized reference to the Axis) is captured by Dick Tracy at the start of the serial, tried and sentenced to death.

However, through the use of a rare drug embedded by his agents in the evening newspaper, he escapes from the gas chamber.

Dick Tracy's G-Men was budgeted at $159,876 although the final negative cost was $163,530 (a $3,654, or 2.3%, overspend).