His best known work is the two volume novel Die Abenteuer des Werner Holt from the early 1960s which had sold over two million copies by his death.
Noll served as a Luftwaffenhelfer in the Schweren Heimatflakbatterie 210 in Borna district of Chemnitz, though at the end of 1944 he became a soldier in the Wehrmacht.
After 1950 he lived in Berlin as a contributing editor of the Bodo Uhse published newspaper Aufbau and an employee of the socialist Neues Deutschland.
Because of his faithfulness to the Socialist Unity Party of Germany, Noll resisted the protest with which numerous East German authors had reacted to the naturalization of Wolf Biermann after 1976.
In May 1979 Noll described in an open letter to Erich Honecker the authors Stefan Heym, Joachim Seyppel and Rolf Schneider as "kaputte Typen" (broken types) who, allegedly, were turning their craving for admiration into no lesser an evil than an actual class enemy might have been.
Dieter Noll was a member of the Schriftstellerverband (Writer's League) of East Germany beginning in 1954, and from 1963 to 1966 was acting chairman of the organization's Berlin chapter.