[2][3][4][5][6] Instrumental in his team under-19 top Italian division title,[3][7] he attracted the attention of several Serie A clubs, eventually joining AS Roma one year after his arrival in Italy.
[2] Brought to the first team squad by José Mourinho, he made his professional debut for Roma on 16 January 2022, replacing Maitland-Niles in the last moments of a 1–0 home Serie A win against Cagliari.
[6] During the 2022–23 season, he was part of Roma's under-19 squad that won the Coppa Italia Primavera, having scored the winning goal in the final against Fiorentina.
[14][15] One month later—on 24 November 2024, Keramitsis was shown a second yellow card during a 0–0 draw played against Elana Toruń in Pogoń's reserve team.
[2][5][7][3] In his early career, his origins and his debut at Roma soon earned him comparisons with the international defender Kostas Manolas.