[1][2] Its jurisdiction covers the civil province of Cádiz south to Guadalete river.

Valdelagrana neighbourhood of El Puerto de Santa María, as it south the River also is included in Cádiz diocese.

Cádiz was raised by Urban IV to episcopal rank in 1263 at the request of king Alfonso X, a year after its Reconquista on the Moors.

The see counted amongst its prelates in 1441 Cardinal Juan de Torquemada, an eminent Dominican theologian jurisconsult, who took a leading part in the Council of Basle and Council of Florence, and defended in his "Summe de Ecclesiâ" the direct power of the pope in temporal matters.

On 1816.01.25, the bishopric lost territory to establish the Apostolic Vicariate of Gibraltar, which had become a British colony.