The first missionaries who came to Nandyal were Arthur Inman and Alfred Briton in the year 1881.

These two missionaries were responsible to establish the SPG High School in 1884 and to build the Holy Cross Church in 1905 in Nandyal.

They learned the local language Telugu and traveled extensively beyond Nandyal to place like Kurnool, Giddalur, Kalasapad, Atmakur and Nandikotkur and planted churches in the villages.

David Gnanamuthu served from 1912 to 1923, he came from Medras Christian Theological College, Madras (1880 to 1885)and he worked in Jammalamadugu area, Koilakuntla, Muhyalapadu, Kurnool and also his son Rev.John Yesudas Gnanamuthu served in this diocese as Deanery Chairman and Archdeacon.

[1] When Dornakal diocese (of which it was then a part) joined the united Church of South India in 1947, Nandyal instead chose to remain in the Indian Anglican Church, under the Diocese of Calcutta.