Its course crosses the municipalities of Saint-Camille, Wotton and Saint-Georges-de-Windsor, in the Les Sources Regional County Municipality (MRC), in the administrative region of Estrie, in Quebec, in Canada.

The main neighboring hydrographic slopes of the Dion river are: The Dion river feeds from various agricultural and forest streams in the sixth rang of the municipality of Saint-Camille.

This head area is located north of the village of Saint-Camille, on the north side of the sixth rang road and south-west of Ham-Sud.

From its head area, the Dion river flows southwest, crossing the sixth rang road, the route 255 and the second road rank.

The toponym "Rivière Dion" was formalized on November 7, 1985, at the Commission de toponymie du Québec.