In the Pteridophyte Phylogeny Group classification of 2016 (PPG I), the family is placed in the suborder Aspleniineae, and includes two genera.

[2] Alternatively, it may be treated as the subfamily Diplaziopsidoideae of a very broadly defined family Aspleniaceae.

[4] Maarten J. M. Christenhusz and Xuan-Chun Zhang originally described the family in 2011 by including three genera Diplaziopsis, Hemidictyum, and Homalosorus.

[1] Two genera are accepted in the PPG I classification, and by the Checklist of Ferns and Lycophytes of the World as of November 2019[update]:[2][4] The following cladogram for the suborder Aspleniineae (as eupolypods II), based on Lehtonen, 2011,[5] and Rothfels & al., 2012,[7] shows a likely phylogenetic relationship between the Diplaziopsidaceae and the other families of the clade.

Cystopteridaceae Rhachidosoraceae Diplaziopsidaceae Aspleniaceae Hemidictyaceae Thelypteridaceae Woodsiaceae Onocleaceae Blechnaceae Athyriaceae