See text Diprotodontidae is an extinct family of large herbivorous marsupials, endemic to Australia and New Guinea during the Oligocene through Pleistocene periods from 28.4 million to 40,000 years ago.

[1] The family primarily consisted of large quadrupedal terrestrial browsers, notably including the largest marsupial that ever lived, the rhino-sized Diprotodon.

Some later diprotodontids from the Pliocene onwards like Ambulator and Diprotodon developed elephant-like forelimbs specialised for walking with modified wristbones which functioned as a heel, along with the development of footpads, which means that the digits probably did not contact the ground, as evidenced by the lack of toes on footprints of Diprotodon.

[4][5] In at least some representatives of the clade, the inside of the skull was lightened by large interior sinus spaces.

The last known members of the group including Diprotodon and Zygomaturus from mainland Australia, and Hulitherium and Maokopia from New Guinea became extinct during the Late Pleistocene around 40,000 years ago as part of the Late Pleistocene megafauna extinctions, following the arrival of humans to Australia-New Guinea.