It originally opened as an enclosed shopping mall in August 1965 with Buttrey Food & Drug, Tempo, and Sprouse-Reitz as anchor stores.

The shopping center is anchored by Big 5 Sporting Goods, Jo-Ann Fabrics and Crafts, Mor Furniture, and Ross.

[1] The mall was completed and opened on August 26, 1965[2] with anchor stores Buttrey Food & Drug, Tempo, and Portland, Oregon-based Sprouse-Reitz.

[5] In 1986, Karcher Mall featured 74 businesses when it was sold from Daum Industries to Los Angeles-based Standard Management Co. for about $14 million.

[8] During the 1990s, the mall lost four anchor stores: Anthony's (1991[9]) Ernst Home Centers (November 1996[1]), Woolworth (July 1997[1]), and The Hub Clothing (1998[10]).

[1] Initial plans for the renovation included adding a new anchor store into the upper level of Emporium, which had been used for warehouse space, and a food court; however, neither of these occurred.

[1] During this period, the mall added Intermountain Sports[12] and Liquidation World to fill the empty spaces left by Woolworth and Ernst respectively.

[15] Just one month after losing Intermountain Sports, Sears relocated to a newly constructed shopping center north of the Karcher Mall.

In late 2001, Ross Dress for Less were added to the former two anchor tenants left by the former Jo-Ann Fabrics and Nampa Furniture, and drywall the interior access from the mall.

[19] Milan Properties also hoped that the new Interstate 84 Interchange and the new nearby Treasure Valley Marketplace would help bring more traffic to the mall.

[21] During 2008, Macy's, which previously operated as The Bon Marché until 2003 and Bon-Macy's until 2005, announced plans to shutter its Karcher Mall location to relocate to the newly constructed Nampa Gateway Center in late 2009.

[23] In September 2009, Northern Light Cinema Grill, an independently owned movie theater and restaurant, opened in the long-vacant Nampa Reel Theatres building.

[29] In July 2019, plans were unveiled for a renovation project that include the demolition of 81,000 square feet (7,500 m2) of the mall's floor area.

[30] Several mall tenants, including anchor stores Big 5 Sporting Goods, Jo-Ann Fabrics, Mor Furniture, and Ross, will remain part of the shopping center after demolition is completed.