TCDD Taşımacılık operates the Southern Kurtalan Express to Ankara[1] or Kurtalan[1] and a daily regional train to Batman.

The station was built by the Turkish State Railways in 1935 as part of the railway from Fevzipaşa.

[2] The station building was built in the Art Deco style, similar to the station buildings of Sivas, Manisa and Malatya.

[3] Diyarbakır station consists of one side platform and one island platform serving three tracks.

A freight yard is also present on the station grounds.