A Russian study from 1979 on djerfisherite from the Kola Peninsula found the formula K6Na(Fe,Cu)24S26Cl, but a study in 2007 of a samples from Siberia found no detectable sodium and states that the formula K6(Fe,Cu,Ni)25S26Cl is considered the most appropriate.

In addition to djerfisherite itself, such minerals also include sodium chvilevaite Na(Cu,Fe,Zn)2S2 and murunskite K2Cu3FeS3.

It was first described in 1966 and named after professor Daniel Jerome Fisher (1896–1988), University of Chicago.

[2] It has been reported from meteorites, copper-nickel hydrothermal deposits, skarn, pegmatite, kimberlites and alkalic intrusive complexes.

Associated minerals include kamacite, troilite, schreibersite, clinoenstatite, tridymite, cristobalite, daubreelite, graphite, roedderite, alabandite, talnakhite, pentlandite, chalcopyrite, magnetite, valleriite, sphalerite and platinum minerals.