[7] Born in Solak, Armenia, to parents from Mush, Gasparyan started to play duduk when he was six.

Creating arrangements for four musicians with "new duduk tones, alto and bass, was an extremely difficult task" and challenge, but the quartet did become a reality performing and "there is no other like it in the world", he witnessed in the liner notes of Nazeli.

[citation needed] He collaborated with many artists, such as Sting, Peter Gabriel, Hossein Alizadeh, Erkan Oğur, Michael Brook, Brian May, Lionel Richie, Derek Sherinian, Roman Miroshnichenko, Ludovico Einaudi, Boris Grebenshchikov, Brian Eno, David Sylvian, Hans Zimmer, and Andreas Vollenweider.

[10] Gasparyan played as part of the Armenian entry "Apricot Stone" by Eva Rivas at the 2010 Eurovision Song Contest in Oslo and became the oldest ever person to feature in a Eurovision Song Contest performance,[11] but was not officially listed as a guest artist.

"[14] Pashinyan called him "an exceptional Armenian intellectual and ranked him among the Greats of the world art; we were proud and inspired by him.

"[15] Catholicos Karekin II, leader of the Armenian Apostolic Church, sent a letter of condolences to his family.

"For decades, he performed the gems of the Armenian music on many stages in Armenia and abroad, serving the grateful mission of recognizing and spreading our culture," read the statement.