The Dnipro Academic Drama and Comedy Theatre (Ukrainian: Дніпровський академічний театр драми і комедії, romanized: Dniprovsʹkyy akademichnyy teatr dramy i komediyi) is a 19th-century city theatre and an architectural monument in the city of Dnipro, Ukraine.

[7] Aleksandr Krasnoselsky's concept, which intended to rebuild the theater in a neoclassical style prior to World War II, was never fully implemented.

[3] The theatre was moved to Barnaul during World War II, and after the Wehrmacht departed the city, the building was bombed and mined.

[9] The theatre's principal director, Anton Serhiiovych Mezhenin, has been carrying on the drama and comedy theatrical traditions since 2021.

[11] The PrizrenFest festival in Kosovo debuted in July 2023 with the performance Maidan Inferno by the Dnipro Academic Theater of Drama and Comedy.