Doña Bárbara is a 1943 Mexican romantic drama film directed and co-written by Fernando de Fuentes and starring María Félix and Julián Soler.

The film is based on the 1929 novel Doña Bárbara by Venezuelan author Rómulo Gallegos, who also co-wrote the screenplay.

Bárbara is an attractive woman raised mostly on the rivers of Venezuela by her riverboat captain father.

She becomes involved with Lorenzo Barquero, the owner of a cattle ranch, with whom she becomes pregnant and has a daughter named Marisela.

Barbara later steals Lorenzo's home and fortune and kicks both him and their daughter out, leaving them to fend for themselves with absolutely nothing.