As a child, Park Hoon (Lee Jong-suk) and his father Park Cheol, a well-known surgeon (Kim Sang-joong) were sent to North Korea to conduct an open-heart surgery on Kim Ill Sung to prevent the Second Korean War.

As the result, he conspired with Jang Seok-joo, a national security official to make Park Cheol and his son trapped in North Korea.

After Park Hoon's father died, he tried to flee to South Korea with Jae-hee, but lost contact with her in the end.

At the same time, Lee Sung-hoon, a leading doctor in the hospital plans his revenge against the institution for the death of his father in the malpractice case 10 years ago.

Director Jin Hyuk previously directed Brilliant Legacy (2009), City Hunter (2011), Master's Sun (2013).