The game and magazine were first released in mid-April 2006 in two 'test-regions' in the United Kingdom and was made available across the UK on 20 September 2006.

However, card 42 featuring "Captain Jack" had a picture change in the national set.

[2] Four special issues have been released (Daleks V.S Cybermen, Invader, Ultimate Monsters and Devastator).

In the game rules section of the official webpage are explained two different versions of the most popular variation of the game, which can be played with the cards included on the magazine or packs bought separately; the first one Bunch of Fives, and the second one Bonus Buster.

This version is a variation of the Bunch of Fives game including bonus cards.

The Annihilator set, comprises 100 cards, taken from the first two series and the 2006 Christmas special The Runaway Bride.

Other cards came from the 2007 Christmas special Voyage of the Damned as well as the first three series of the revamped show.

The most recent release is the Devastator set which is based on the 2007 Christmas Special and the 2008 series of Doctor Who.

A special issue with four free packs and a series 4 guide was also released on 17 September 2008 priced £4.99.

A special edition pack of cards on The Sarah Jane Adventures came with Issue 62 as a one-off set.

It was titled the "golden ticket" on the packets, this being because the back of the card was partially gold.