The Dodge Ram VTS was painted Banzai Blue with dual white skunk stripes, housed an 8.0 L (488 cid) V10, a six-speed Borg-Warner manual gearbox, and 17 in (432 mm) Viper GTS wheels wrapped in BF Goodrich 275/60-HR17 Comp T/A HR4 tires.

The cast aluminum cylinder block had cast-iron liners and cross-bolted main caps.

Bilstein shock absorbers, performance-tuned springs and unique aerodynamic aids were used to enhance the Ram SRT-10's higher-speed performance.

Large chrome SRT-10 logos were mounted to the driver and passenger side doors and rear tailgate right side on the Quad cab and Single Cab 2005 models replaced in 2006 by smaller chrome and red SRT-10 logo badges .

Another exterior feature was a tonneau cover with an attached spoiler that was supposed to come standard on the 2005 Quad Cab version and all 2006 models, but due to manufacturing problems was not installed on nearly half of the Ram SRT-10s intended.

To help remedy this situation, Dodge added a $1000 credit and a regular spoiler to the Ram SRT-10s that did not receive the tonneau cover.

In addition to style, the spoiler also helped with air flow and provided a reduction in lift and drag.

The Truck audio had 3 options of the Dodge Ram SRT-10 by 2006 and consisted of 8 Infinity brand speakers with a DVD based large color LCD map navigation system and a mid-tier CD turn by turn graphics CD-based system with small color LCD, and finally a standard LED Radio with CD player; all built and designed by Infinity audio and 10 inch woofer mounted in between the seats with silver bezel and 575 watts of total system output, Bluetooth by U-Connect for hands free communication through your car stereo as a factory option also full digital Satellite radio.

Taking a cue from the Dodge Viper, the Ram SRT-10 came with a red start button on the dash.

The Quad Cab was fitted with a 4.56 final-drive gear ratio to improve low-end acceleration and was rated at 7,500 lb (3,402 kg) towing capacity.

The Quad Cab was only offered with a 4-speed automatic transmission (the 48RE borrowed from the Heavy Duty with the Cummins ISB turbo-diesel).

In July 2004, a Dodge Ram SRT-10, driven by NASCAR driver Brendan Gaughan set both the Guinness World Record and Sports Car Club of America's record for the world's fastest production truck[9] with an average speed of 154.587 mph (248.784 km/h).