Domingo Santa María González (Latin American Spanish: [doˈmiŋgo ˈsanta maˈɾi.a]; August 4, 1825 – July 18, 1889) was a Chilean political figure.

He completed his early studies in the Instituto Nacional, and graduated as a lawyer from the Universidad de Chile in 1847.

At the same time, he became the secretary of the Sociedad del Orden (Society for Public Order), a liberal club opposed to the conservative party.

His active intervention in rigging elections in favor of the conservatives made him into the principal target of the opposition.

In 1858, he was elected to the lower house of congress and a year later, he was forced into exile in Europe as a result of the 1859 revolution.

A few months prior to his presidency Chile had captured Lima and Santa María's administration forced Peru to sign the Treaty of Ancón (October 29, 1883), putting an end to war.

He centralized the railroads into a state holding, inaugurated the first telephonic line between Santiago and Concepcion, and introduced the first public electric lighting.

Santa María's presidency was also marked by increased electoral fraud and intervention in favor of the government liberals.

I can see this well and I will impose myself to govern as well as I can and I will support as many liberal laws as are presented to prepare the ground for a future democracy.

I belong to the old guard and if I participate in intervention it is because I want an effective, disciplined Parliament that collaborates with the government's work for the common good.