The Dominican Church and Monastery (Ukrainian: Домініканський костел і монастир, romanized: Dominikanskyi kostel i monastyr, Polish: Kościół i klasztor Dominikanów we Lwowie) in Lviv, Ukraine is located in the city's Old Town, east of the market square.

The Dominican Order first arrived in Lviv during the 13th century and the first wooden church is said to have been built in 1234 within the Low Castle, founded by the wife of Leo I of Halych.

In 1749 Józef Potocki laid the cornerstone for the present day Baroque church, commonly attributed to Jan de Witte.

Between 1756 and 1761 Mikołaj Bazyli Potocki donated 236,000 złoty to the church and the Dominican monastery in Lviv, where his mother was buried.

Before 1946, the church contained a miraculous icon of the Blessed Virgin Mary, crowned by Pope Benedict XIV in 1751, which can be found today in the Dominican Basilica of St. Nicholas in Gdańsk, and an alabaster figure brought by St. Hyacinth from Mongol-sacked Kiev to Halych and later to Lviv, which now resides in Church of St. Giles in Kraków.