Prince Dominik Hieronim Radziwiłł (Lithuanian: Dominykas Jeronimas Radvila; Belarusian: Дамінік Геранім Радзівіл; Polish: Dominik Hieronim Radziwiłł; 4 August 1786 – 11 November 1813) was a Polish-Lithuanian nobleman who was Ordynat of Nesvizh and Olyka and owner of Biržai, Dubingiai, Słuck and Kapyl estates.

He was the only son of Prince Hieronim Wincenty Radziwiłł (1759–1786) and his wife, Princess Sophie Friederike of Thurn and Taxis (1758–1800), of the Nesvizh line of the family.

Only because of Prussia's intervention (since Dominik's cousin, Antoni Radziwiłł, was married to a Prussian princess) were the Radziwiłłs able to keep the family trust properties, while Mir Castle and 18,000 km2 of land passed to Dominik's only legitimate child, Princess Stephania Radziwill (1809–1832), who had to marry a Russian subject, according to the Czar's order, whom she found in German Prince Ludwig zu Sayn-Wittgenstein-Sayn.

The castle then passed to her daughter Princess Marie zu Sayn-Wittgenstein-Sayn (1829–1897), wife of German chancellor Chlodwig, Prince of Hohenlohe-Schillingsfürst, who was forced to sell it as a foreigner, according to newly introduced law, at the end of the 19th century.

The ordynat of Nesvizh and Olyka fell into the hands of the younger Kletsk line, Dominik's cousin, Prince Antoni Radziwiłł.