[8] Gutiérrez graduated from Horizon Christian Academy in San Diego, where he played safety on the school's football team, and attended Southwestern College in Chula Vista for a few semesters.

[10] He made two more appearances in 2006, first at WrestleMania 22 with Angie and Aalyah watching his father win the World Heavyweight Championship for the first time and second on the September 15 episode of SmackDown!

He once again appeared on the March 12, 2010, episode of SmackDown, this time during the feud between Rey Mysterio and the Straight Edge Society (CM Punk, Luke Gallows, and Serena).

[13] On the March 19, 2019, episode of SmackDown Live, Dominik appeared on the show with his father, Rey Mysterio, who announced that he would be facing Samoa Joe for the WWE United States Championship at WrestleMania 35 on April 7.

[23] On the following episode of Raw, Dominik lost to Rollins in a qualifier for the triple threat match for the WWE Championship at Clash of Champions.

[34] On the February 21 episode of Raw, The Miz challenged The Mysterios to a tag team match at WrestleMania 38 with social media personality Logan Paul as his partner, which they accepted.

[37] On the June 27 episode of Raw, The Mysterios competed in a Money in the Bank qualifying battle royal, which was won by Riddle.

[38] In the summer of 2022, The Mysterios began feuding with The Judgment Day (Finn Bálor, Damian Priest and Rhea Ripley) over their attempts to recruit Dominik into the group and betray his father.

[39] After losing an Undisputed WWE Tag Team Championship match on the following episode of Raw, The Judgment Day attacked Dominik and Rey.

After the match, Dominik hit Edge with a low blow and a clothesline to Rey, turning heel for the first time in his career.

[49] On Night 1 of WrestleMania 39 on April 1, Rey defeated Dominik after interference from the newly-reformed Latino World Order and Bad Bunny.

[51] On the July 17 episode of Raw, Dominik and Priest failed to win the Undisputed WWE Tag Team Championship from Kevin Owens and Sami Zayn.

At NXT The Great American Bash on July 30, Dominik successfully defended the title against Lee and Mustafa Ali in a triple threat match.

[62] At Survivor Series WarGames on November 25, Dominik participated in his first WarGames match alongside The Judgment Day (which now included JD McDonagh) and Drew McIntyre against Cody Rhodes, Jey Uso, Seth "Freakin" Rollins, Sami Zayn and the returning Randy Orton in a losing effort.

[65] At WrestleMania XL Night 1 on April 6, Dominik teamed up with Legado Del Fantasma's Santos Escobar against his father, Rey, and Andrade in a losing effort after interference from Lane Johnson and Jason Kelce.

[66] On the April 15 episode of Raw, Dominik suffered a legitimate elbow injury during a match with Andrade, and was believed to be out of in ring action for “about six to eight weeks”.

[67][68] During this time, he began a storyline with Liv Morgan, having accidentally helped her defeat Becky Lynch to win the Women's Championship at King and Queen of the Ring on May 25.

Dominik won the match by pinning his father - a first in his wrestling career - and almost kissed Morgan after, but they were interrupted by a returning Ripley.