[3] In 1987, she obtained a diploma in property management from the La Fédération Nationale de l'Immobilier (FNAIM) in Paris, before receiving training as a real estate expert in 1989.

[3][8] In 1996, Ouattara was appointed CEO of French hair care chain EJD Inc.,[3] a company that manages the Jacques Dessange Institute in Washington, D.C.

[9] Following her husband's election as President of Ivory Coast, and in accordance with campaign pledges he had made, Ouattara ceased her activities as a business leader and resigned from all her professional duties.

Built on a 4.9-hectare (12-acre) plot, the hospital has a capacity of 130 beds and is meant help to improve access to healthcare for women, and reduce maternal and child mortality.

[14] It is part of a project of the Foundation to open three shelters in strategic areas of the Ivory Coast (Soubré, Bouaké and Ferkéssédougo),  in order to assist children engaged into trafficking and exploitation before reintegration into their families.

The committee's activities have led to the adoption of two National Action Plans (2012-2014 and 2015-2017) to reduce the worst forms of child labor in the country.

[23] On 18 December 2014, Dominique Ouattara was appointed Joint United Nations Programme on HIV/AIDS Special Ambassador for the elimination of mother-to-child transmission of HIV and the promotion of pediatric treatment.

[3] Their son, Loic Folloroux, was Director of the West African branch of the Armajaro Limited group, a company specializing in trading in cocoa and raw materials.

[27][28] She married Ouattara, then Deputy Governor of the BCEAO in Dakar, on August 24, 1991 in the Town Hall of the 16th arrondissement of Paris in the presence of family friends like Martin Bouygues and Jean-Christophe Mitterrand.