Many of the early releases were by American artists who in the US were signed to Drag City (Smog, Will Oldham, Royal Trux), a relationship which continues to this day.

Recent high-profile releases from Anna Calvi, Franz Ferdinand, Arctic Monkeys, and The Kills have only acted as a catalyst to this, and Domino is now one of the longest running and most successful independent record labels in the UK.

There were a number of new releases, as well as a compilation album and a series of gigs in London under the 'Worlds of Possibility' banner, to celebrate the label's first decade in October of that year.

In March 2021, it was announced that seminal shoegaze band My Bloody Valentine had signed with the label.

[7] As well as new music, Domino have released compilations by British post-punk bands such as Orange Juice, Josef K, Fire Engines and Young Marble Giants.