]The town is located on the Moskva-Oka plain, in the center of the East European Plain, south-east of the capital, 37 km from the center of Moscow, on the Moscow – Kashira highway and the Paveletsky suburban railway line, near the federal highway, M-4 "Don".

The name of the modern town, Domodedovo which was incorporated in 1900, was given after nearby village with the same name, was first mentioned around 1401 in the spiritual literacy of Vladimir the Bold, Prince of Serpukhov and Borovski.

In 1781, during the administrative reform of Catherine II a city called Nikitsk was founded on site Kolychёva village and was a district seat in the Moscow Governorate.

In 2007, a referendum on the building of a toll motorway within the city limits took place, where 95% of the inhabitants voted against.

[12] A group of residents of Domodedovo have announced the establishment of the "Russian Democratic Republic"[13] and asked the European Union for official recognition.

[1] The administrative division was established on 1 April 2011 as a result of abolishing Domodedovsky District, the territory of which was re-organized as the town under oblast jurisdiction.