[2] Domoni was already a flourishing centre for trade in the 15th century with Africa, Persia, Arab countries, and India.

It is home to a significant chirazienne (Shirazi) population who are descents of Sunni aristocratic immigrants from Shiraz, Persia, between the 14th and 18th centuries.

[5] Infighting among the chiefs of Anjouan resulted in their making an appeal to Europeans to broker a peace deal.

Protective walls built as fortifications around the town were meant to prevent attacks by Malagasy pirates.

[16]The middle section of the town, known as Hari ya Muzhi, was the centre of activity from the 16th century onwards.

It is the zone where the main plaza, the Friday mosque and a large number of mansions of the town are located.

The mausoleum of president Ahmed Abdallah Abderemane, who was assassinated in 1989 by a presidential guard, is white in colour and includes four tall minarets.

[11] A colourful sight seen in the town is of women dabbing sandalwood paste on each other's faces while sitting on the staircase of the houses.

[17] Women create music by using coconut shells, gongs, and sticks, as well as playing the tari (frame drum); men play on different musical instruments such as the fumba, dori, and msindio (drums), along with the gabus (lute), mzumara (double reed), nkayamba (rattle), and ndzedze (box zither).

[18] Wedding ceremonies feature a performance, a type of bullfight, evidence of the historical presence of the Portuguese at Domoni.

In one incident the father of a Christian leader had to pay a fine and the family live in exile from Domoni for a month.