A remix of the song's B-side, "Stoned", by American electronic music duo Deep Dish topped the US Billboard Dance Club Play chart.

[2] The song is set in common time composed in a moderate tempo of 80 beats per minute,[3] written in F♯ major with a vocal range from the tone of F♯4 to the note of C♯6.

[3] The Jake Nava-directed music video for "Don't Leave Home" starts with the singer driving on a desert road as it gets dark.

Some of the themes and scenery imply drug addiction, like the hazy affects, the forest filled with mushrooms and hallucinations of spiders and snakes.

"Stoned" was remixed by Deep Dish; this version peaked at number one on the US Billboard Dance Club Play chart on the week dated 24 January 2004.