Don Alonzo Joshua Upham (May 1, 1809 – July 19, 1877) was an American lawyer, Democratic politician, and Wisconsin pioneer.

He served as the 4th Mayor of Milwaukee and was the Democratic nominee for Governor of Wisconsin in the 1851 election.

[5] In 1837, Upham traveled west, eventually settling in the village of Milwaukee in the Wisconsin Territory, where he continued to work as a lawyer.

[8] Upham was the Democratic nominee for Governor of Wisconsin in 1851, but fell 507 votes short of Whig candidate Leonard J.

Upham House, is listed on the National Register of Historic Places.