Don Orsillo (born December 16, 1968) is an American sportscaster who is the play-by-play announcer for the San Diego Padres of Major League Baseball (MLB).

[1] Orsillo was the play-by-play announcer for the Boston Red Sox on NESN from 2001 to 2015; he was hired by the Padres to replace Dick Enberg upon his retirement at the end of the 2016 season.

[6] Orsillo was NESN's play-by-play man from the beginning of the 2001 season (his first game included a no-hitter thrown by then Red Sox pitcher Hideo Nomo against the Baltimore Orioles).

In 2009, Remy was out for the season due to health problems, and Orsillo worked with various color commentators, including Dennis Eckersley, Nick Cafardo, Sean Casey, Dave Roberts and Frank Viola.

[11][12] The Red Sox and NESN were further criticized in 2022 when Orsillo was not included in an April 20 tribute ceremony at Fenway Park for longtime broadcast partner Remy, who died the previous October.

[15] In addition to his Red Sox duties, Orsillo has called the Beanpot hockey tournament and Boston College Eagles men's basketball on NESN.

His first call was the 2007 National League wild card playoff between the Colorado Rockies and San Diego Padres, with Joe Simpson serving as his color man.

[16] When Johnson was given his studio hosting duties back, Orsillo became a permanent member of the postseason team in 2020, working alongside analyst Jeff Francoeur until 2022, when he was replaced by Bob Costas.