Donald James Cram (April 22, 1919 – June 17, 2001) was an American chemist who shared the 1987 Nobel Prize in Chemistry with Jean-Marie Lehn and Charles J. Pedersen "for their development and use of molecules with structure-specific interactions of high selectivity."
He grew up on Aid to Dependent Children, and learned to work at an early age, doing jobs such as picking fruit, tossing newspapers, and painting houses, while bartering for piano lessons.
[3] Cram attended the Winwood High School in Long Island, N.Y.[4] From 1938 to 1941, he attended Rollins College in Winter Park, Florida on a national honorary scholarship, where he worked as an assistant in the chemistry department, and was active in theater, chapel choir, Lambda Chi Alpha, Phi Society, and Zeta Alpha Epsilon.
[3] Cram expanded upon Charles Pedersen's ground-breaking synthesis of crown ethers, two-dimensional organic compounds that are able to recognize and selectively combine with the ions of certain metal elements.
Cram's work represented a large step toward the synthesis of functional laboratory-made mimics of enzymes and other natural molecules whose special chemical behavior is due to their characteristic structure.
[2] He showed a self-deprecating style, saying at one time: An investigator starts research in a new field with faith, a foggy idea, and a few wild experiments.